This is something that, in hindsight, could have been pieced together a while back, but it’s still good to confirm because it’s reassuring to see Marvel Studios and Sony working so diligently on creating an authentic Spider-verse within the MCU. The new and official Spider-Man: Homecoming app provides some pretty cool features, one of which is the ability to read some select text messages between Peter and his friends. In one exchange between Peter and his best friend Ned (Jacob Batalon), Ned notes that one of their teachers, Ms. Warren, is getting concerned with the amount of school Peter has been missing:

We’ve known for a while now that Ms. Warren would be played by Selenis Leyva (Orange is the New Black), but we now have confirmation that she is one of Peter’s teachers. A quick check of the first trailer reveals that she is one of Peter’s science teachers (he does go to a STEM academy, so he may have more than one) and that really makes it seem like Marvel and Sony are seeding Spidey’s garden.

Fans of the Spidey comics will undoubtedly recognize the surname of Warren as it ties to one of the most bizarre tangents of Spidey’s long history: the Clone Saga. In that arc, Miles Warren/The Jackal, a professor at Empire State University with a shady history and interest in illegal cloning activities, discovered Peter was Spider-Man and cloned him producing several clones including ongoing characters Kaine and Ben Reilly.  Now despite some confusing retcons in the comics, this Ms. Warren probably isn’t that Warren, but they might be related.

In The Amazing Spider-Man #8 (an issue that also introduced the Living Brain and teased the revelation of Peter as Spidey), one of Peter’s high school science teachers was a Mr. Warren, created by Stan Lee and written in a bit part. In The Amazing Spider-Man #31, Peter met a college biology professor also named Warren who went on to become the cloning creep described above. New writer Gerry Conway meant for this Warren to be the same one from Peter’s high school days, but it seems as though the official Marvel word is that they are two different people, though “Mr. Warren” is the brother of “Professor Warren.” Phew…

With that out of the way, it would be a nice nod to the original Spidey comics for Ms. Warren to have an older sibling working at Empire State University, setting up a potentially crazy arc for future films. The Clone Saga has always been a source of debate for Spidey fans, but nobody could debate that if Marvel and Sony are looking to distance themselves from the previous Spidey films, this would definitely do it.

Source: Reddit